TPDB

3D PDB MODEL

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TPDB ID TPDB48888

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 58-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

KENITPWIYSMKQPVSCNREHSEIGICLSGIDDDIQNDGKCWKFCLMVAKSGGYNADK

FASTA

>TPDB48888|Antifungal|length=58
KENITPWIYSMKQPVSCNREHSEIGICLSGIDDDIQNDGKCWKFCLMVAKSGGYNADK

Formula C283H441N77O89S6

Absent Amino Acids

Common Amino Acids IK

Mass 6538.44

PI 5.53

Basic Residues 8

Acidic Residues 8

Hydrophobic Residues 19

Net Charge -1

Boman Index 13.19

Hydrophobicity -0.538

Aliphatic Index 67.24

Half Life

Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 14230

Absorbance 280nm 217.64

Polar Residues 18

number

2

A

1

R

4

N

5

D

4

C

3

E

2

Q

5

G

1

H

6

I

2

L

6

K

2

M

1

F

2

P

5

S

1

T

2

W

2

Y

2

V

Amino Acid Distribution

A: 2 R: 1 N: 4 D: 5 C: 4 E: 3 Q: 2 G: 5 H: 1 I: 6 L: 2 K: 6 M: 2 F: 1 P: 2 S: 5 T: 1 W: 2 Y: 2 V: 2

Length

58

Formula

C283H441N77O89S6

Mass

6538.44

PI

5.53

Net Charge

-1

Boman Index

13.19

Hydrophobicity

-0.538

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.