TPDB

3D PDB MODEL

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TPDB ID TPDB48883

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 74-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

IITKTMNSKETIYLDNPAVSPSIDQNLVDIHLGHSFVQGVMSFCYDCGKACFRRGKNLARCQKFVCRCTISKLR

FASTA

>TPDB48883|Antifungal|length=74
IITKTMNSKETIYLDNPAVSPSIDQNLVDIHLGHSFVQGVMSFCYDCGKACFRRGKNLARCQKFVCRCTISKLR

Formula C364H590N106O104S8

Absent Amino Acids W

Common Amino Acids CIKS

Mass 8371.82

PI 9.18

Basic Residues 13

Acidic Residues 5

Hydrophobic Residues 27

Net Charge +6

Boman Index 11.43

Hydrophobicity -0.093

Aliphatic Index 81.62

Half Life

Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour

Extinction Coefficient Cystines 3355

Absorbance 280nm 40.07

Polar Residues 25

number

3

A

5

R

4

N

4

D

6

C

1

E

3

Q

4

G

2

H

6

I

5

L

6

K

2

M

4

F

2

P

6

S

4

T

0

W

2

Y

5

V

Amino Acid Distribution

A: 3 R: 5 N: 4 D: 4 C: 6 E: 1 Q: 3 G: 4 H: 2 I: 6 L: 5 K: 6 M: 2 F: 4 P: 2 S: 6 T: 4 W: 0 Y: 2 V: 5

Length

74

Formula

C364H590N106O104S8

Mass

8371.82

PI

9.18

Net Charge

+6

Boman Index

11.43

Hydrophobicity

-0.093

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.