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Peptide record

TPDB48882

Antifungal standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB48882
Antifungal
Anti-infective peptides
AFP-GFuse
standard
No
A 20-aa standard natural antifungal peptide sequence curated from AFP-GFuse, with an available 3D structural model.
Sequence
KEPRLLCRQCVRMILNVEKL
Physicochemical Analysis
C105H189N33O27S3
ADGHFSTWY
L
2442.04
9.92
5
2
8
+3
6.78
-0.095
126.50
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
125
5.12
4
Residue Composition
number
0
A
3
R
1
N
0
D
2
C
2
E
1
Q
0
G
0
H
1
I
4
L
2
K
1
M
0
F
1
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 0 C: 2 E: 2 Q: 1 G: 0 H: 0 I: 1 L: 4 K: 2 M: 1 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
20
C105H189N33O27S3
2442.04
9.92
+3
6.78
-0.095
Evidence Records 5 records
Evidence 1 Activity

Activity

MIC
Antifungal
4-64 µM

Target

B. cereus

Source & Reference

NA

Other

inhibited Gram+ B. cereus (MIC 4-64 uM) and S-aureus(MIC > 64 uM), Gram- E. coli (MIC 8 uM), MDR P. aeruginosa (MIC 4-64 uM), and
Evidence 2 Activity

Activity

MIC
Antifungal
8 µM

Target

Escherichia coli

Source & Reference

NA

Other

inhibited Gram+ B. cereus (MIC 4-64 uM) and S-aureus(MIC > 64 uM), Gram- E. coli (MIC 8 uM), MDR P. aeruginosa (MIC 4-64 uM), and fungi C. albicans (MIC 32 uM) and filamentous fungu
Evidence 3 Activity

Activity

MIC
Antifungal
4-64 µM

Target

Pseudomonas aeruginosa

Source & Reference

NA

Other

ed Gram+ B. cereus (MIC 4-64 uM) and S-aureus(MIC > 64 uM), Gram- E. coli (MIC 8 uM), MDR P. aeruginosa (MIC 4-64 uM), and fungi C. albicans (MIC 32 uM) and filamentous fungus F. oxysporum (MIC 64 uM).
Evidence 4 Activity

Activity

MIC
Antifungal
32 µM

Target

Candida albicans

Source & Reference

NA

Other

aureus(MIC > 64 uM), Gram- E. coli (MIC 8 uM), MDR P. aeruginosa (MIC 4-64 uM), and fungi C. albicans (MIC 32 uM) and filamentous fungus F. oxysporum (MIC 64 uM).
Evidence 5 Activity

Activity

MIC
Antifungal
64 µM

Target

F. oxysporum

Source & Reference

NA

Other

MDR P. aeruginosa (MIC 4-64 uM), and fungi C. albicans (MIC 32 uM) and filamentous fungus F. oxysporum (MIC 64 uM).