TPDB

3D PDB MODEL

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TPDB ID TPDB48879

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 46-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

MTEQKPKPSCHNVMVGNYVPTASDRAANRTLGFGLVTNIINGGLDC

FASTA

>TPDB48879|Antifungal|length=46
MTEQKPKPSCHNVMVGNYVPTASDRAANRTLGFGLVTNIINGGLDC

Formula C208H338N62O66S4

Absent Amino Acids W

Common Amino Acids NG

Mass 4891.59

PI 8.28

Basic Residues 5

Acidic Residues 3

Hydrophobic Residues 16

Net Charge +1

Boman Index 8.40

Hydrophobicity -0.213

Aliphatic Index 74.13

Half Life

Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 1615

Absorbance 280nm 33.02

Polar Residues 15

number

3

A

2

R

5

N

2

D

2

C

1

E

1

Q

5

G

1

H

2

I

3

L

2

K

2

M

1

F

3

P

2

S

4

T

0

W

1

Y

4

V

Amino Acid Distribution

A: 3 R: 2 N: 5 D: 2 C: 2 E: 1 Q: 1 G: 5 H: 1 I: 2 L: 3 K: 2 M: 2 F: 1 P: 3 S: 2 T: 4 W: 0 Y: 1 V: 4

Length

46

Formula

C208H338N62O66S4

Mass

4891.59

PI

8.28

Net Charge

+1

Boman Index

8.40

Hydrophobicity

-0.213

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.