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Peptide record

TPDB48872

Antifungal standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB48872
Antifungal
Anti-infective peptides
AFP-GFuse
standard
No
A 21-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, with an available 3D structural model.
Sequence
GVCRYHRQKWRTRGREWLRRC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C120H192N48O27S2
ANDIMFPS
R
2803.27
12.02
9
1
5
+7
5.32
-1.771
32.38
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
12615
4.50
5
Residue Composition
number
0
A
7
R
0
N
0
D
2
C
1
E
1
Q
2
G
1
H
0
I
1
L
1
K
0
M
0
F
0
P
0
S
1
T
2
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 7 N: 0 D: 0 C: 2 E: 1 Q: 1 G: 2 H: 1 I: 0 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 1 W: 2 Y: 1 V: 1
Chemical Descriptors
21 reviewed residue count
C120H192N48O27S2 sequence-only estimate (linear, free termini)
2803.27 sequence-only estimate (linear, free termini)
12.02 sequence-only estimate (linear, free termini)
+7 sequence-only estimate (linear, free termini)
5.32 sequence-only estimate (linear, free termini)
-1.771 sequence-only estimate (linear, free termini)
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antifungal
4.25 µM

Target

v. Holcicola

Source & Reference

NA

Other

Gram- X. campestris pv. Holcicola (MIC 4.25 uM), X. oryzae pv. oryzicola (MIC 17 uM), X. oryzae pv. oryzae (MIC 17 uM), and X. oryzae pv.
Evidence 2 Activity

Activity

MIC
Antifungal
17 µM

Target

v. oryzicola

Source & Reference

NA

Other

Gram- X. campestris pv. Holcicola (MIC 4.25 uM), X. oryzae pv. oryzicola (MIC 17 uM), X. oryzae pv. oryzae (MIC 17 uM), and X. oryzae pv. oryzae (MIC 8.5 uM). They can cause
Evidence 3 Activity

Activity

MIC
Antifungal
17 µM

Target

v. oryzae

Source & Reference

NA

Other

. campestris pv. Holcicola (MIC 4.25 uM), X. oryzae pv. oryzicola (MIC 17 uM), X. oryzae pv. oryzae (MIC 17 uM), and X. oryzae pv. oryzae (MIC 8.5 uM). They can cause a serious blight of rice.
Evidence 4 Activity

Activity

MIC
Antifungal
8.5 µM

Target

v. oryzae

Source & Reference

NA

Other

M), X. oryzae pv. oryzicola (MIC 17 uM), X. oryzae pv. oryzae (MIC 17 uM), and X. oryzae pv. oryzae (MIC 8.5 uM). They can cause a serious blight of rice.