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Peptide record

TPDB48871

Antifungal standard
57 amino acids
Basic Information
3D PDB MODEL
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TPDB48871
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 57-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
RTTTGGSPGYGIGGRTKTCFTPALCIYRGVHGCDSYCKTKNFDYGYCRQEHCCCVNY
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C269H405N79O82S8
MW
G
6314.14
8.30
9
3
14
+4
1.84
-0.519
32.46
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
9440
1.50
26
Residue Composition
number
1
A
4
R
2
N
2
D
8
C
1
E
1
Q
9
G
2
H
2
I
1
L
3
K
0
M
2
F
2
P
2
S
7
T
0
W
6
Y
2
V
Amino Acid Distribution
A: 1 R: 4 N: 2 D: 2 C: 8 E: 1 Q: 1 G: 9 H: 2 I: 2 L: 1 K: 3 M: 0 F: 2 P: 2 S: 2 T: 7 W: 0 Y: 6 V: 2
Chemical Descriptors
57 reviewed residue count
C269H405N79O82S8 sequence-only estimate (linear, free termini)
6314.14 sequence-only estimate (linear, free termini)
8.30 sequence-only estimate (linear, free termini)
+4 sequence-only estimate (linear, free termini)
1.84 sequence-only estimate (linear, free termini)
-0.519 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.