TPDB

3D PDB MODEL

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TPDB ID TPDB48871

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 57-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

RTTTGGSPGYGIGGRTKTCFTPALCIYRGVHGCDSYCKTKNFDYGYCRQEHCCCVNY

FASTA

>TPDB48871|Antifungal|length=57
RTTTGGSPGYGIGGRTKTCFTPALCIYRGVHGCDSYCKTKNFDYGYCRQEHCCCVNY

Formula C269H405N79O82S8

Absent Amino Acids MW

Common Amino Acids G

Mass 6314.14

PI 8.30

Basic Residues 9

Acidic Residues 3

Hydrophobic Residues 14

Net Charge +4

Boman Index 5.23

Hydrophobicity -0.519

Aliphatic Index 32.46

Half Life

Mammalian: 1 hour Yeast: 2 min E.coli: 2 min

Extinction Coefficient Cystines 9440

Absorbance 280nm 149.51

Polar Residues 26

number

1

A

4

R

2

N

2

D

8

C

1

E

1

Q

9

G

2

H

2

I

1

L

3

K

0

M

2

F

2

P

2

S

7

T

0

W

6

Y

2

V

Amino Acid Distribution

A: 1 R: 4 N: 2 D: 2 C: 8 E: 1 Q: 1 G: 9 H: 2 I: 2 L: 1 K: 3 M: 0 F: 2 P: 2 S: 2 T: 7 W: 0 Y: 6 V: 2

Length

57

Formula

C269H405N79O82S8

Mass

6314.14

PI

8.30

Net Charge

+4

Boman Index

5.23

Hydrophobicity

-0.519

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.