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Peptide record

TPDB48866

Antifungal standard
49 amino acids
Basic Information
3D PDB MODEL
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TPDB48866
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 49-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
DKRCSIIIDLSPCYPIECRLSCITERNGDGECVVSKVGSTPNCLCTYDC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C222H364N62O76S8
AQHMFW
C
5374.18
4.45
5
7
13
-2
1.73
-0.020
81.43
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
3480
0.65
20
Residue Composition
number
0
A
3
R
2
N
4
D
8
C
3
E
0
Q
3
G
0
H
5
I
3
L
2
K
0
M
0
F
3
P
5
S
3
T
0
W
2
Y
3
V
Amino Acid Distribution
A: 0 R: 3 N: 2 D: 4 C: 8 E: 3 Q: 0 G: 3 H: 0 I: 5 L: 3 K: 2 M: 0 F: 0 P: 3 S: 5 T: 3 W: 0 Y: 2 V: 3
Chemical Descriptors
49 reviewed residue count
C222H364N62O76S8 sequence-only estimate (linear, free termini)
5374.18 sequence-only estimate (linear, free termini)
4.45 sequence-only estimate (linear, free termini)
-2 sequence-only estimate (linear, free termini)
1.73 sequence-only estimate (linear, free termini)
-0.020 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.