TPDB

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

TPDB ID TPDB48864

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 56-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

ITVQADCIGPCNDDCQQLCKSKGYTDWTCASFRTKSSCCCKPPRHQIFEQNAQLNN

FASTA

>TPDB48864|Antifungal|length=56
ITVQADCIGPCNDDCQQLCKSKGYTDWTCASFRTKSSCCCKPPRHQIFEQNAQLNN

Formula C262H411N79O86S8

Absent Amino Acids M

Common Amino Acids C

Mass 6300.10

PI 7.49

Basic Residues 7

Acidic Residues 5

Hydrophobic Residues 13

Net Charge +1

Boman Index 11.63

Hydrophobicity -0.675

Aliphatic Index 45.36

Half Life

Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour

Extinction Coefficient Cystines 7490

Absorbance 280nm 118.89

Polar Residues 27

number

3

A

2

R

4

N

4

D

8

C

1

E

6

Q

2

G

1

H

3

I

2

L

4

K

0

M

2

F

3

P

4

S

4

T

1

W

1

Y

1

V

Amino Acid Distribution

A: 3 R: 2 N: 4 D: 4 C: 8 E: 1 Q: 6 G: 2 H: 1 I: 3 L: 2 K: 4 M: 0 F: 2 P: 3 S: 4 T: 4 W: 1 Y: 1 V: 1

Length

56

Formula

C262H411N79O86S8

Mass

6300.10

PI

7.49

Net Charge

+1

Boman Index

11.63

Hydrophobicity

-0.675

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.