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Peptide record

TPDB48863

Antifungal standard
60 amino acids
Basic Information
3D PDB MODEL
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TPDB48863
Antifungal
Anti-infective peptides
AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia
standard
No
A 60-aa standard-residue antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.
Sequence
ALSFLFLFLFVAQEIVVTEANTCEHLADTYRGVCFTDASCDDHCKNKAHLISGTCHNFKC
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C296H448N78O88S6
MPW
ACLF
6699.64
5.62
8
7
25
-3
1.01
0.262
81.33
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
1865
0.28
19
Residue Composition
number
6
A
1
R
3
N
4
D
6
C
3
E
1
Q
2
G
4
H
2
I
6
L
3
K
0
M
6
F
0
P
3
S
5
T
0
W
1
Y
4
V
Amino Acid Distribution
A: 6 R: 1 N: 3 D: 4 C: 6 E: 3 Q: 1 G: 2 H: 4 I: 2 L: 6 K: 3 M: 0 F: 6 P: 0 S: 3 T: 5 W: 0 Y: 1 V: 4
Chemical Descriptors
60 reviewed residue count
C296H448N78O88S6 sequence-only estimate (linear, free termini)
6699.64 sequence-only estimate (linear, free termini)
5.62 sequence-only estimate (linear, free termini)
-3 sequence-only estimate (linear, free termini)
1.01 sequence-only estimate (linear, free termini)
0.262 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.