TPDB

3D PDB MODEL

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TPDB ID TPDB48863

Activity

Antifungal

Activity_category_statistics

Anti-infective peptides

Database_Source

AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 60-aa standard natural antifungal peptide sequence curated from AFP-GFuse, Antifungipept, CAFPdb, and other sources, with an available 3D structural model.

Sequence

ALSFLFLFLFVAQEIVVTEANTCEHLADTYRGVCFTDASCDDHCKNKAHLISGTCHNFKC

FASTA

>TPDB48863|Antifungal|length=60
ALSFLFLFLFVAQEIVVTEANTCEHLADTYRGVCFTDASCDDHCKNKAHLISGTCHNFKC

Formula C296H448N78O88S6

Absent Amino Acids MPW

Common Amino Acids ACLF

Mass 6699.64

PI 5.62

Basic Residues 8

Acidic Residues 7

Hydrophobic Residues 25

Net Charge -3

Boman Index 7.67

Hydrophobicity 0.262

Aliphatic Index 81.33

Half Life

Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour

Extinction Coefficient Cystines 1865

Absorbance 280nm 27.84

Polar Residues 19

number

6

A

1

R

3

N

4

D

6

C

3

E

1

Q

2

G

4

H

2

I

6

L

3

K

0

M

6

F

0

P

3

S

5

T

0

W

1

Y

4

V

Amino Acid Distribution

A: 6 R: 1 N: 3 D: 4 C: 6 E: 3 Q: 1 G: 2 H: 4 I: 2 L: 6 K: 3 M: 0 F: 6 P: 0 S: 3 T: 5 W: 0 Y: 1 V: 4

Length

60

Formula

C296H448N78O88S6

Mass

6699.64

PI

5.62

Net Charge

-3

Boman Index

7.67

Hydrophobicity

0.262

Evidence 1 Activity

Source & Reference

Database Source dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label	Source Definition
Antifungal	dbAMP classified under the Anti-fungal function class.