Back to search

Peptide record

TPDB48226

peptide 20 ACE inhibitors Antihypertensive Cell-penetrating Peptides standard
5 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB48226
peptide 20
ACE inhibitors Antihypertensive Cell-penetrating Peptides
Cardiometabolic peptides Delivery and barrier-penetrating peptides
FermFooDB Peptipedia AHTPDB AHTpin CPPsite3.0
standard
No
A 5-aa standard natural multi-activity (ACE inhibitors, Antihypertensive, and Cell-penetrating Peptides) peptide sequence curated from FermFooDB, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
RPKHP
Physicochemical Analysis
C28H47N11O6
ANDCEQGILMFSTWYV
P
633.75
11.49
3
0
0
+2
3.66
-2.960
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
0
I
0
L
1
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 1 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C28H47N11O6
633.75
11.49
+2
3.66
-2.960
Free
L
Linear
Free
N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells And J774.2 Mouse Macrophage Cell Lines.

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
5-FAM at N terminal
Cytoplasm
All the peptides tested were internalised into the cells
Endocytosis
In vitro
CCSSSCCCCCSCC
Additional Detail Fields 1 fields
CCSSSCCCCCSCC