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Peptide record

TPDB48222

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) ACE inhibitors Antihypertensive iDPPIV standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB48222
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
ACE inhibitors Antihypertensive iDPPIV
Cardiometabolic peptides
FermFooDB Peptipedia AHTPDB AHTpin iDPPIV
standard
No
A 4-aa standard natural multi-activity (ACE inhibitors, Antihypertensive, and iDPPIV) peptide sequence curated from FermFooDB, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
VLGP
Physicochemical Analysis
C18H32N4O5
ARNDCEQHIKMFSTWY
GLPV
384.48
6.02
0
0
2
-0
-0.03
1.500
170.00
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
1
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
4
C18H32N4O5
384.48
6.02
-0
-0.03
1.500
384.4692
384.2365
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
580.40 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Nongonierma A. B., FitzGerald R. J.
Inhibition of dipeptidyl peptidase IV (DPP-IV) by proline containing casein-derived peptides. J. Funct. Foods, 5, 1909-1917
2013
Journal

Other

4
Additional Detail Fields 1 fields
4