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Peptide record

TPDB48206

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) Antihypertensive Bitter iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB48206
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
Antihypertensive Bitter iDPPIV
Cardiometabolic peptides Food sensory peptides
AHTPDB Peptipedia Tastepeptides-Meta iDPPIV
standard
No
A 2-aa standard natural multi-activity (Antihypertensive, Bitter, and iDPPIV) peptide sequence curated from AHTPDB, Peptipedia, Tastepeptides-Meta, and other sources, with an available 3D structural model.
Sequence
IQ
Physicochemical Analysis
C11H21N3O4
ARNDCEGHLKMFPSTWYV
QI
259.31
6.02
0
0
1
-0
0.27
0.500
195.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
1
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C11H21N3O4
259.31
6.02
-0
0.27
0.500
259.3013
259.1527
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Lan V. T. T., Ito K., Ohno M., Motoyama T., Ito S., Kawarasaki Y.
Analyzing a dipeptide library to identify human dipeptidyl peptidase IV inhibitor. Food Chemistry 175, 66-73, 2015
2015
Journal

Other

2
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CCC(=O)N)C(=O)O InChI=1S/C11H21N3O4/c1-3-6(2)9(13)10(16)14-7(11(17)18)4-5-8(12)15/h6-7,9H,3-5,13H2,1-2H3,(H2,12,15)(H,14,16)(H,17,18)/t6-,7-,9-/m0/s1 InChIKey=CNPNWGHRMBQHBZ-ZKWXMUAHSA-N Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acids (ID 490) the ChEMBL database
Additional Detail Fields 1 fields
2