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Peptide record

TPDB48204

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) Antihypertensive Bitter iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB48204
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
Antihypertensive Bitter iDPPIV
Cardiometabolic peptides Food sensory peptides
AHTPDB Peptipedia Tastepeptides-Meta iDPPIV
standard
No
A 2-aa standard natural multi-activity (Antihypertensive, Bitter, and iDPPIV) peptide sequence curated from AHTPDB, Peptipedia, Tastepeptides-Meta, and other sources, with an available 3D structural model.
Sequence
IN
Physicochemical Analysis
C10H19N3O4
ARDCEQGHLKMFPSTWYV
NI
245.28
6.02
0
0
1
-0
0.11
0.500
195.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C10H19N3O4
245.28
6.02
-0
0.11
0.500
245.2748
245.1371
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Lan V. T. T., Ito K., Ohno M., Motoyama T., Ito S., Kawarasaki Y.
Analyzing a dipeptide library to identify human dipeptidyl peptidase IV inhibitor. Food Chemistry 175, 66-73, 2015
2015
Journal

Other

2
BIOPEP-UWM database of bioactive peptides SMILES: N[C@@]([H])([C@]([H])(CC)C)C(=O)N[C@@]([H])(CC(=O)N)C(=O)O InChI=1S/C10H19N3O4/c1-3-5(2)8(12)9(15)13-6(10(16)17)4-7(11)14/h5-6,8H,3-4,12H2,1-2H3,(H2,11,14)(H,13,15)(H,16,17)/t5-,6-,8-/m0/s1 InChIKey=HZYHBDVRCBDJJV-HAFWLYHUSA-N Inhibitor of Angiotensin-converting enzyme (EC 3.4.15.1) (MEROPS ID: M02-001) according to the AHTPDB database Bitter peptide according to the BIOPEP-UWM database of sensory peptides and amino acides (ID 488)
Additional Detail Fields 1 fields
2