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Peptide record

TPDB48203

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) ACE inhibitors Antihypertensive Bitter iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB48203
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
ACE inhibitors Antihypertensive Bitter iDPPIV
Cardiometabolic peptides Food sensory peptides
FermFooDB Peptipedia AHTPDB Tastepeptides-Meta iDPPIV
standard
No
A 2-aa standard natural multi-activity (ACE inhibitors, Antihypertensive, Bitter, and other sources) peptide sequence curated from FermFooDB, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
II
Physicochemical Analysis
C12H24N2O3
ARNDCEQGHLKMFPSTWYV
I
244.33
6.02
0
0
2
-0
-0.62
4.500
390.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C12H24N2O3
244.33
6.02
-0
-0.62
4.500
244.3296
244.1781
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Lan V. T. T., Ito K., Ohno M., Motoyama T., Ito S., Kawarasaki Y.
Analyzing a dipeptide library to identify human dipeptidyl peptidase IV inhibitor. Food Chemistry 175, 66-73
2015
Journal

Other

2
BIOPEP database of bioactive peptides SMILES: N[C@H](C(=O)N[C@H](C(=O)O)[C@H](CC)C)[C@H](CC)C InChI=1S/C12H24N2O3/c1-5-7(3)9(13)11(15)14-10(12(16)17)8(4)6-2/h7-10H,5-6,13H2,1-4H3,(H,14,15)(H,16,17)/t7-,8-,9-,10-/m0/s1 InChIKey: BCVIOZZGJNOEQS-XKNYDFJKSA-N Activator of u-Plasminogen activator (EC 3.4.21.73) (MEROPS ID: S01.231) according to BRENDA database Glucose uptake stimulating peptide according to BIOPEP database of bioactive peptides (ID 8325) Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001) according to AHTPDB database Inhibitor of citrulline uptake in yeasts according to ChEMBL database Bitter peptide according to BIOPEP database of sensory peptides and amino acids
Additional Detail Fields 1 fields
2