Peptide record

TPDB48200

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) Antihypertensive Bitter iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB48200
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
Antihypertensive Bitter iDPPIV
Cardiometabolic peptides Food sensory peptides
AHTPDB Peptipedia Tastepeptides-Meta iDPPIV
standard
No
A 2-aa standard natural multi-activity (Antihypertensive, Bitter, and iDPPIV) peptide sequence curated from AHTPDB, Peptipedia, Tastepeptides-Meta, and other sources, with an available 3D structural model.
Sequence
AL
Physicochemical Analysis
C9H18N2O3
RNDCEQGHIKMFPSTWYV
AL
202.25
6.02
0
0
2
-0
-0.73
2.800
245.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C9H18N2O3
202.25
6.02
-0
-0.73
2.800
202.2501
202.1313
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
882.13 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Nongonierma A. B., Mooney C., Shields D. C., FitzGerald R. J.
Inhibition of dipeptidyl peptidase IV and xanthine oxidase by amino acids and dipeptides. Food Chemistry, 141, 644-653.
2013
Journal

Other

2
Additional Detail Fields 1 fields
2