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Peptide record

TPDB48146

ACE Inhibitor ACE inhibitors Antihypertensive standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB48146
ACE Inhibitor
ACE inhibitors Antihypertensive
Cardiometabolic peptides
Peptipedia AHTPDB AHTpin
standard
No
A 4-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from Peptipedia, AHTPDB, and AHTpin, with an available 3D structural model.
Sequence
ALEP
Physicochemical Analysis
C19H32N4O7
RNDCQGHIKMFSTWYV
AELP
428.49
3.29
0
1
2
-1
1.74
0.125
122.50
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
4
C19H32N4O7
428.49
3.29
-1
1.74
0.125
428.4787
428.2263
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
6320.00 µM
ACE inhibitor
ah

Source & Reference

NA
Vecchi B., Añón M. C.
ACE inhibitory tetrapeptides from Amaranthus hypochondriacus 11S globulin. Phytochemistry, 70, 864-870
2009
Journal

Other

4
Evidence 2 Activity

Activity

IC50
Antihypertensive
6320.00 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Vecchi B., Añón M. C.
ACE inhibitory tetrapeptides from Amaranthus hypochondriacus 11S globulin. Phytochemistry, 70, 864-870
2009
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
4
Additional Detail Fields 1 fields
4