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Peptide record

TPDB48127

Ac-LVE ACE inhibitor from pearl oyster ACE inhibitors Antihypertensive Selfassembly standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB48127
Ac-LVE ACE inhibitor from pearl oyster
ACE inhibitors Antihypertensive Selfassembly
Cardiometabolic peptides Self-assembling and biomaterial peptides
Peptipedia AHTPDB AHTpin SAPdb
standard
No
A 3-aa standard natural multi-activity (ACE inhibitors, Antihypertensive, and Selfassembly) peptide sequence curated from Peptipedia, AHTPDB, AHTpin, and other sources, with an available 3D structural model.
Sequence
LVE
Physicochemical Analysis
C16H29N3O6
ARNDCQGHIKMFPSTWY
ELV
359.42
3.29
0
1
2
-1
1.53
1.500
226.67
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
3
C16H29N3O6
359.42
3.29
-1
1.53
1.500
359.4168
359.2049
Self-Assembly Information 1 records
Record 1 Selfassembly

Source

29018249
10.1016/j.compbiomed.2021.104391
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly

Self-Assembly

Nanostructure formation
Hydrogel Hydrogels
temperature: Room temperature solvent: acetonitrile/water and formic acid concentration: 0.10%
Selfassembly; Nanostructure=Hydrogel; Hydrogels; Trigger=temperature: Room temperature; solvent: acetonitrile/water and formic acid; concentration: 0.10%
Field emission scanning electron microscopy (FESEM)
Selfassembly
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
14.20 µM
ACE inhibitor
ah

Source & Reference

NA
Qian Z.-L., Jung W.-K., Lee S.-H., Byun H.-G., Kim S.-K.
Antihypertensive effect of an angiotensin I-converting enzyme inhibitory peptide from bulfrog (Rana catesbeiana Shaw) muscle protein in spontaneously hypertensive rats. Process Biochemistry, 42, 1443-1448
2007
Journal

Other

3
Evidence 2 Activity

Activity

IC50
Antihypertensive
14.20 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Qian Z.-L., Jung W.-K., Lee S.-H., Byun H.-G., Kim S.-K.
Antihypertensive effect of an angiotensin I-converting enzyme inhibitory peptide from bulfrog (Rana catesbeiana Shaw) muscle protein in spontaneously hypertensive rats. Process Biochemistry, 42, 1443-1448
2007
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
3
Evidence 3 Selfassembly

Activity

Nanostructure formation
Selfassembly Nanostructure=Hydrogel Hydrogels Trigger=temperature: Room temperature solvent: acetonitrile/water and formic acid concentration: 0.10%
Hydrogel Hydrogels

Source & Reference

SAPdb
10.1016/j.compbiomed.2021.104391

Other

None specified
temperature: Room temperature solvent: acetonitrile/water and formic acid concentration: 0.10%
Field emission scanning electron microscopy (FESEM)
29018249
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
Additional Detail Fields 6 fields
temperature: Room temperature solvent: acetonitrile/water and formic acid concentration: 0.10%
None specified
SAPdb ID NA low-detail seed row from experimentally curated self-assembly database.
3
29018249
SAPdb: A database of short peptides and the corresponding nanostructures formed by self-assembly