Peptide record

TPDB48083

ACE inhibitor ACE inhibitors Antihypertensive standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB48083
ACE inhibitor
ACE inhibitors Antihypertensive
Cardiometabolic peptides
Peptipedia AHTPDB AHTpin
standard
No
A 4-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from Peptipedia, AHTPDB, and AHTpin, with an available 3D structural model.
Sequence
VVRP
Physicochemical Analysis
C21H39N7O5
ANDCEQGHILKMFSTWY
V
469.58
11.05
1
0
2
+1
1.40
0.575
145.00
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
4
C21H39N7O5
469.58
11.05
+1
1.40
0.575
469.5767
469.3004
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
81.00 µM
ACE inhibitor
ah

Source & Reference

NA
Murray B.A., FitzGerald R. J.
Angiotensin converting enzyme inhibitory peptides derived from food proteins: biochemistry, bioactivity and production. Curr. Pharm. Des., 2007, 13, 773-791.
2007
Journal

Other

4
Evidence 2 Activity

Activity

IC50
Antihypertensive
81.00 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Murray B.A., FitzGerald R. J.
Angiotensin converting enzyme inhibitory peptides derived from food proteins: biochemistry, bioactivity and production. Curr. Pharm. Des., 2007, 13, 773-791.
2007
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
4
Additional Detail Fields 1 fields
4