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Peptide record

TPDB48056

dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) Antihypertensive Umami iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB48056
dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
Antihypertensive Umami iDPPIV
Cardiometabolic peptides Food sensory peptides
AHTPDB AHTpin Peptipedia Tastepeptides-Meta iDPPIV
standard
No
A 2-aa standard natural multi-activity (Antihypertensive, Umami, and iDPPIV) peptide sequence curated from AHTPDB, AHTpin, Peptipedia, and other sources, with an available 3D structural model.
Sequence
EP
Physicochemical Analysis
C10H16N2O5
ARNDCQGHILKMFSTWYV
EP
244.25
3.29
0
1
0
-1
2.47
-2.550
0.00
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
1
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
2
C10H16N2O5
244.25
3.29
-1
2.47
-2.550
244.2438
244.1055
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Hikida A., Ito K., Motoyama T., Kato R., Kawarasaki Y.
Systematic analysis of a dipeptide library for inhibitor development using human dipeptidyl peptidase IV produced by a Saccharomyces cerevisiae expression system. Biochemical and Biophysical Research Communications 430, 1217-1222.
2013
Journal

Other

2
Additional Detail Fields 1 fields
2