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Peptide record

TPDB48021

ACE inhibitor from edible mushroom (Agaricus bisporus) ACE inhibitors Antihypertensive standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB48021
ACE inhibitor from edible mushroom (Agaricus bisporus)
ACE inhibitors Antihypertensive
Cardiometabolic peptides
Peptipedia AHTPDB AHTpin
standard
No
A 5-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from Peptipedia, AHTPDB, and AHTpin, with an available 3D structural model.
Sequence
PSSNK
Physicochemical Analysis
C21H37N7O9
ARDCEQGHILMFTWYV
S
531.57
10.10
1
0
0
+1
2.12
-2.120
0.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
3
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
0
F
1
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 1 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C21H37N7O9
531.57
10.10
+1
2.12
-2.120
531.5585
531.2644
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
129.30 µM
ACE inhibitor
ah

Source & Reference

NA
Lau C.C., Abdullah N., Shuib A.S., Aminudin N.
Novel angiotensin I-converting enzyme inhibitory peptides derived from edible mushroom Agaricus bisporus (J.E. Lange) Imbach identified by LC–MS/MS. Food Chemistry 148, 396-401.
2014
Journal

Other

5
Evidence 2 Activity

Activity

IC50
Antihypertensive
129.30 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Lau C.C., Abdullah N., Shuib A.S., Aminudin N.
Novel angiotensin I-converting enzyme inhibitory peptides derived from edible mushroom Agaricus bisporus (J.E. Lange) Imbach identified by LC–MS/MS. Food Chemistry 148, 396-401.
2014
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
5
Additional Detail Fields 1 fields
5