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Peptide record

TPDB48020

ACE inhibitor from edible mushroom (Agaricus bisporus) ACE inhibitors Antihypertensive standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB48020
ACE inhibitor from edible mushroom (Agaricus bisporus)
ACE inhibitors Antihypertensive
Cardiometabolic peptides
Peptipedia AHTPDB AHTpin
standard
No
A 5-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from Peptipedia, AHTPDB, and AHTpin, with an available 3D structural model.
Sequence
RIGLF
Physicochemical Analysis
C29H48N8O6
ANDCEQHKMPSTWYV
RGILF
604.75
11.05
1
0
3
+1
-1.18
1.240
156.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
1
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 1 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C29H48N8O6
604.75
11.05
+1
-1.18
1.240
604.7395
604.3686
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
115.90 µM
ACE inhibitor
ah

Source & Reference

NA
Lau C.C., Abdullah N., Shuib A.S., Aminudin N.
Novel angiotensin I-converting enzyme inhibitory peptides derived from edible mushroom Agaricus bisporus (J.E. Lange) Imbach identified by LC–MS/MS. Food Chemistry 148, 396-401.
2014
Journal

Other

5
Evidence 2 Activity

Activity

IC50
Antihypertensive
115.90 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Lau C.C., Abdullah N., Shuib A.S., Aminudin N.
Novel angiotensin I-converting enzyme inhibitory peptides derived from edible mushroom Agaricus bisporus (J.E. Lange) Imbach identified by LC–MS/MS. Food Chemistry 148, 396-401.
2014
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
5
Additional Detail Fields 1 fields
5