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Peptide record

TPDB47980

ACE inhibitor Antihypertensive Bitter standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB47980
ACE inhibitor
Antihypertensive Bitter
Cardiometabolic peptides Food sensory peptides
AHTPDB Peptipedia Tastepeptides-Meta
standard
No
A 3-aa standard natural multi-activity (Antihypertensive and Bitter) peptide sequence curated from AHTPDB, Peptipedia, and Tastepeptides-Meta, with an available 3D structural model.
Sequence
PGR
Physicochemical Analysis
C13H24N6O4
ANDCEQHILKMFSTWYV
RGP
328.37
11.05
1
0
0
+1
1.27
-2.167
0.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
3
C13H24N6O4
328.37
11.05
+1
1.27
-2.167
328.3665
328.1854
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
Antihypertensive
0.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

AHTPDB
Escudero E., Sentandreu M. A., Arihara K., Toldrá F.
Angiotensin I-converting enzyme inhibitory peptides generated from in vitro gastrointestinal digestion of pork meat. J. Agric. Food Chem., 58, 2895-2901, 2010
2010
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
3
BIOPEP-UWM database of bioactive peptides SMILES: N1[C@@]([H])(CCC1)C(=O)NCC(=O)N[C@@]([H])(CCCNC(=N)N)C(=O)O InChI=1S/C13H24N6O4/c14-13(15)17-6-2-4-9(12(22)23)19-10(20)7-18-11(21)8-3-1-5-16-8/h8-9,16H,1-7H2,(H,18,21)(H,19,20)(H,22,23)(H4,14,15,17)/t8-,9-/m0/s1 InChIKey=DMKWYMWNEKIPFC-IUCAKERBSA-N
Additional Detail Fields 1 fields
3