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Peptide record

TPDB47954

ACE inhibitor ACE inhibitors Antihypertensive standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB47954
ACE inhibitor
ACE inhibitors Antihypertensive
Cardiometabolic peptides
Peptipedia AHTPDB AHTpin
standard
No
A 5-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from Peptipedia, AHTPDB, and AHTpin, with an available 3D structural model.
Sequence
KAPVA
Physicochemical Analysis
C22H40N6O6
RNDCEQGHILMFSTWY
A
484.60
10.10
1
0
3
+1
1.17
0.460
98.00
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
5
C22H40N6O6
484.60
10.10
+1
1.17
0.460
484.5880
484.3000
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
46.56 µM
Inhibitor of Angiotensin-Converting Enzyme
ACE inhibitor
ah

Source & Reference

NA
Escudero E., Sentandreu M. A., Arihara K., Toldrá F.
Angiotensin I-converting enzyme inhibitory peptides generated from in vitro gastrointestinal digestion of pork meat. J. Agric. Food Chem., 58, 2895-2901
2010
Journal

Other

5
Evidence 2 Activity

Activity

IC50
Antihypertensive
46.56 µM
Inhibitor of Angiotensin-Converting Enzyme
ACE inhibitor
ah

Source & Reference

AHTPDB
Escudero E., Sentandreu M. A., Arihara K., Toldrá F.
Angiotensin I-converting enzyme inhibitory peptides generated from in vitro gastrointestinal digestion of pork meat. J. Agric. Food Chem., 58, 2895-2901
2010
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
5
Additional Detail Fields 1 fields
5