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Peptide record

TPDB47950

ACE inhibitor from k-CN (76-80) ACE inhibitors Antihypertensive standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB47950
ACE inhibitor from k-CN (76-80)
ACE inhibitors Antihypertensive
Cardiometabolic peptides
Peptipedia AHTPDB AHTpin
standard
No
A 5-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from Peptipedia, AHTPDB, and AHTpin, with an available 3D structural model.
Sequence
PNSHP
Physicochemical Analysis
C23H34N8O8
ARDCEQGILKMFTWYV
P
550.57
7.85
1
0
0
+0
2.41
-2.140
0.00
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
0
0.00
2
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
1
H
0
I
0
L
0
K
0
M
0
F
2
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 0 M: 0 F: 0 P: 2 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
5
C23H34N8O8
550.57
7.85
+0
2.41
-2.140
550.5635
550.2492
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
1001.00 µM
ACE inhibitor
ah

Source & Reference

NA
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

5
EC50 >1000
Evidence 2 Activity

Activity

IC50
Antihypertensive
1001.00 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
5
EC50 >1000
Additional Detail Fields 1 fields
5