Peptide record

TPDB47924

ACE inhibitor ACE inhibitors Antihypertensive standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB47924
ACE inhibitor
ACE inhibitors Antihypertensive
Cardiometabolic peptides
Peptipedia AHTPDB AHTpin
standard
No
A 5-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from Peptipedia, AHTPDB, and AHTpin, with an available 3D structural model.
Sequence
AVVRP
Physicochemical Analysis
C24H44N8O6
NDCEQGHILKMFSTWY
V
540.66
11.05
1
0
3
+1
1.23
0.820
136.00
Mammalian: 4.4 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
0
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
5
C24H44N8O6
540.66
11.05
+1
1.23
0.820
540.6544
540.3374
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
74.00 µM
ACE inhibitor
ah

Source & Reference

NA
Murray B.A., FitzGerald R. J.
Angiotensin converting enzyme inhibitory peptides derived from food proteins: biochemistry, bioactivity and production. Curr. Pharm. Des., 2007, 13, 773-791.
2007
Journal

Other

5
Evidence 2 Activity

Activity

IC50
Antihypertensive
74.00 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Murray B.A., FitzGerald R. J.
Angiotensin converting enzyme inhibitory peptides derived from food proteins: biochemistry, bioactivity and production. Curr. Pharm. Des., 2007, 13, 773-791.
2007
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
5
Additional Detail Fields 1 fields
5