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Peptide record

TPDB47896

ACE inhibitor ACE inhibitors Antihypertensive standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB47896
ACE inhibitor
ACE inhibitors Antihypertensive
Cardiometabolic peptides
Peptipedia AHTPDB AHTpin
standard
No
A 5-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from Peptipedia, AHTPDB, and AHTpin, with an available 3D structural model.
Sequence
SKVYP
Physicochemical Analysis
C28H44N6O8
ARNDCEQGHILMFTW
KPSYV
592.69
9.74
1
0
2
+1
0.70
-0.680
58.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
1490
251.39
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
0
F
1
P
1
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 1 S: 1 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
5
C28H44N6O8
592.69
9.74
+1
0.70
-0.680
592.6826
592.3210
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
1.40 µM
ACE inhibitor
ah

Source & Reference

NA
Korhonen H., Pihlanto A.
Technological options for the production of health-promoting proteins and peptides derived from milk and colostrum. Curr. Pharm. Des., 13,
2007
Journal

Other

5
IC50 (EC50) value in mg/mL
Evidence 2 Activity

Activity

IC50
Antihypertensive
1.40 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Korhonen H., Pihlanto A.
Technological options for the production of health-promoting proteins and peptides derived from milk and colostrum. Curr. Pharm. Des., 13,
2007
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
5
IC50 (EC50) value in mg/mL
Additional Detail Fields 1 fields
5