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Peptide record

TPDB47712

ACE inhibitor ACE inhibitors Antihypertensive standard
3 amino acids
Basic Information
3D PDB MODEL
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TPDB47712
ACE inhibitor
ACE inhibitors Antihypertensive
Cardiometabolic peptides
Peptipedia AHTPDB AHTpin
standard
No
A 3-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from Peptipedia, AHTPDB, and AHTpin, with an available 3D structural model.
Sequence
LVY
Physicochemical Analysis
C20H31N3O5
ARNDCEQGHIKMFPSTW
LYV
393.48
5.94
0
0
3
-0
-1.43
2.233
226.67
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
1490
378.67
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
3
C20H31N3O5
393.48
5.94
-0
-1.43
2.233
393.4760
393.2256
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
5.84 µM
ACE inhibitor
ah

Source & Reference

NA
Ren Y., Wang Q., Chen S., Cao H.
Integrating Computational Modeling and Experimental Assay to Discover New Potent ACE-Inhibitory Peptides. Molecular Informatics 33, 43-52, DOI: 10.1002/minf.201300131.
2014
Journal

Other

3
Evidence 2 Activity

Activity

IC50
Antihypertensive
5.84 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Ren Y., Wang Q., Chen S., Cao H.
Integrating Computational Modeling and Experimental Assay to Discover New Potent ACE-Inhibitory Peptides. Molecular Informatics 33, 43-52, DOI: 10.1002/minf.201300131.
2014
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
3
Additional Detail Fields 1 fields
3