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Peptide record

TPDB47706

ACE inhibitor (fr. of beta-casein, 140-143) ACE inhibitors Antihypertensive Neuropeptide iDPPIV standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB47706
ACE inhibitor (fr. of beta-casein, 140-143)
ACE inhibitors Antihypertensive Neuropeptide iDPPIV
Cardiometabolic peptides Neuroactive peptides
Peptipedia AHTPDB AHTpin iDPPIV
standard
No
A 4-aa standard natural multi-activity (ACE inhibitors, Antihypertensive, Neuropeptide, and other sources) peptide sequence curated from Peptipedia, AHTPDB, AHTpin, and other sources, with an available 3D structural model.
Sequence
LQSW
Physicochemical Analysis
C25H36N6O7
ARNDCEGHIKMFPTYV
QLSW
532.60
6.02
0
0
2
-0
-1.70
-0.350
97.50
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
5500
1032.68
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
4
C25H36N6O7
532.60
6.02
-0
-1.70
-0.350
532.5879
532.2637
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
500.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

NA
Maeno M., Yamamoto N., Takano T.
Identification of an antihypertensive peptide from casein hydrolysate produced by a proteinase from Lactobacillus helveticus CP790. J. Dairy Sci., 79, 1316-1321, 1996
1996
Journal

Other

4
AHTPDB: ID 1167, 1729, 3390, 4094, 4166, 4896, 4987, 6053, 6378 ChemSpider: ID 7982838 EROP-Moscow: ID E10826 FeptideDB: ID 3397 MBPDB: Peptide LQSW PubChem: CID 9807079 SATPdb: ID satpdb19983
Evidence 2 Activity

Activity

IC50
Antihypertensive
500.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: M02-001)
ACE inhibitor
ah

Source & Reference

AHTPDB
Maeno M., Yamamoto N., Takano T.
Identification of an antihypertensive peptide from casein hydrolysate produced by a proteinase from Lactobacillus helveticus CP790. J. Dairy Sci., 79, 1316-1321, 1996
1996
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
4
AHTPDB: ID 1167, 1729, 3390, 4094, 4166, 4896, 4987, 6053, 6378 ChemSpider: ID 7982838 EROP-Moscow: ID E10826 FeptideDB: ID 3397 MBPDB: Peptide LQSW PubChem: CID 9807079 SATPdb: ID satpdb19983
Additional Detail Fields 1 fields
4