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Peptide record

TPDB47580

ACE inhibitor from garlic dipeptidyl peptidase IV inhibitor (DPP IV inhibitor) ACE inhibitors Antihypertensive Neuropeptide Umami iDPPIV standard
2 amino acids
Basic Information
3D PDB MODEL
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TPDB47580
ACE inhibitor from garlic dipeptidyl peptidase IV inhibitor (DPP IV inhibitor)
ACE inhibitors Antihypertensive Neuropeptide Umami iDPPIV
Cardiometabolic peptides Neuroactive peptides Food sensory peptides
Peptipedia AHTPDB AHTpin Tastepeptides-Meta iDPPIV
standard
No
A 2-aa standard natural multi-activity (ACE inhibitors, Antihypertensive, Neuropeptide, and other sources) peptide sequence curated from Peptipedia, AHTPDB, AHTpin, and other sources, with an available 3D structural model.
Sequence
NY
Physicochemical Analysis
C13H17N3O5
ARDCEQGHILKMFPSTWV
NY
295.30
5.94
0
0
1
-0
-0.52
-2.400
0.00
Mammalian: 1.4 hour Yeast: 3 min E.coli: >10 hour
1490
504.58
2
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
2
C13H17N3O5
295.30
5.94
-0
-0.52
-2.400
295.2905
295.1164
Evidence Records 3 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
32.60 µM
ACE inhibitor
ah

Source & Reference

NA
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

2
Evidence 2 Activity

Activity

IC50
Antihypertensive
32.60 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
2
Evidence 3 Activity

Activity

IC50
iDPPIV
0.00 µM
Inhibitor of Dipeptidyl Peptidase IV (EC 3.4.14.5) (MEROPS ID: S09.003)
dipeptidyl peptidase IV inhibitor
dpp

Source & Reference

iDPPIV
Lan V. T. T., Ito K., Ohno M., Motoyama T., Ito S., Kawarasaki Y.
Analyzing a dipeptide library to identify human dipeptidyl peptidase IV inhibitor. Food Chemistry 175, 66-73
2015
Journal

Other

2
Additional Detail Fields 1 fields
2