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Peptide record

TPDB47575

ACE inhibitor from as2-casein ACE inhibitors Antihypertensive standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB47575
ACE inhibitor from as2-casein
ACE inhibitors Antihypertensive
Cardiometabolic peptides
FermFooDB Peptipedia AHTPDB AHTpin
standard
No
A 4-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from FermFooDB, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
VRYL
Physicochemical Analysis
C26H43N7O6
ANDCEQGHIKMFPSTW
RLYV
549.67
9.88
1
0
3
+1
-0.62
0.550
170.00
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
1490
271.07
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
4
C26H43N7O6
549.67
9.88
+1
-0.62
0.550
549.6612
549.3265
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
24.10 µM
ACE inhibitor
ah

Source & Reference

FermFooDB
Murray B.A., FitzGerald R. J.
Angiotensin converting enzyme inhibitory peptides derived from food proteins: biochemistry, bioactivity and production. Curr. Pharm. Des., 2007, 13, 773-791.
2007
Journal

Other

4
Produced by synthesis.
Evidence 2 Activity

Activity

IC50
Antihypertensive
24.10 µM
ACE inhibitor
ah

Source & Reference

AHTPDB FermFooDB
Murray B.A., FitzGerald R. J.
Angiotensin converting enzyme inhibitory peptides derived from food proteins: biochemistry, bioactivity and production. Curr. Pharm. Des., 2007, 13, 773-791.
2007
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
4
Produced by synthesis.
Additional Detail Fields 1 fields
4