Peptide record

TPDB47527

ACE inhibitor ACE inhibitors Antihypertensive standard
3 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB47527
ACE inhibitor
ACE inhibitors Antihypertensive
Cardiometabolic peptides
Peptipedia AHTPDB AHTpin
standard
No
A 3-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from Peptipedia, AHTPDB, and AHTpin, with an available 3D structural model.
Sequence
IWH
Physicochemical Analysis
C23H30N6O4
ARNDCEQGLKMFPSTYV
HIW
454.53
7.85
1
0
2
+0
-1.20
0.133
130.00
Mammalian: 20 hour Yeast: 30 min E.coli: >10 hour
5500
1210.04
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
1
H
1
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
3
C23H30N6O4
454.53
7.85
+0
-1.20
0.133
454.5209
454.2322
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
3.50 µM
ACE inhibitor
ah

Source & Reference

NA
Loponen J.
Angiotensin converting enzyme inhibitory peptides in Finnish cereals: a database survey. Agric. Food Sci., 2004, 13, 39-45.
2004
Journal

Other

3
Evidence 2 Activity

Activity

IC50
Antihypertensive
3.50 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Loponen J.
Angiotensin converting enzyme inhibitory peptides in Finnish cereals: a database survey. Agric. Food Sci., 2004, 13, 39-45.
2004
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
3
Additional Detail Fields 1 fields
3