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Peptide record

TPDB47490

ACE inhibitor from caprine b-Lg ACE inhibitors Antihypertensive standard
4 amino acids
Basic Information
3D PDB MODEL
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TPDB47490
ACE inhibitor from caprine b-Lg
ACE inhibitors Antihypertensive
Cardiometabolic peptides
Peptipedia AHTPDB AHTpin
standard
No
A 4-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from Peptipedia, AHTPDB, and AHTpin, with an available 3D structural model.
Sequence
LQKW
Physicochemical Analysis
C28H43N7O6
ARNDCEGHIMFPSTYV
QLKW
573.69
10.10
1
0
2
+1
-0.84
-1.125
97.50
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
5500
958.70
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
1
L
1
K
0
M
0
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
4
C28H43N7O6
573.69
10.10
+1
-0.84
-1.125
573.6826
573.3265
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
35.00 µM
ACE inhibitor
ah

Source & Reference

NA
Murray B.A., FitzGerald R. J.
Angiotensin converting enzyme inhibitory peptides derived from food proteins: biochemistry, bioactivity and production. Curr. Pharm. Des., 2007, 13, 773-791.
2007
Journal

Other

4
Produced by thermolysin.
Evidence 2 Activity

Activity

IC50
Antihypertensive
35.00 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Murray B.A., FitzGerald R. J.
Angiotensin converting enzyme inhibitory peptides derived from food proteins: biochemistry, bioactivity and production. Curr. Pharm. Des., 2007, 13, 773-791.
2007
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
4
Produced by thermolysin.
Additional Detail Fields 1 fields
4