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Peptide record

TPDB47423

ACE inhibitor from b-CN (46-59) rat ACE inhibitors Antihypertensive standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB47423
ACE inhibitor from b-CN (46-59) rat
ACE inhibitors Antihypertensive
Cardiometabolic peptides
pep-lab Peptipedia AHTPDB AHTpin
standard
No
A 14-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from pep-lab, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
KFHSGIQSEPKAIP
Physicochemical Analysis
C70H111N19O20
RNDCLMTWYV
IKPS
1538.77
9.88
3
1
4
+1
4.79
-0.686
62.86
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
1
Q
1
G
1
H
2
I
0
L
2
K
0
M
1
F
2
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 1 H: 1 I: 2 L: 0 K: 2 M: 0 F: 1 P: 2 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C70H111N19O20
1538.77
9.88
+1
4.79
-0.686
1538.7412
1537.8227
Evidence Records 2 records
Evidence 1 Activity

Activity

EC50
ACE inhibitors
1001.00 µM
ACE inhibitor
ah

Source & Reference

NA
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

14
EC50>1000
Evidence 2 Activity

Activity

EC50
Antihypertensive
1001.00 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
14
EC50>1000
Additional Detail Fields 1 fields
14