Back to search

Peptide record

TPDB47422

ACE inhibitor from b-CN (48-59) rat ACE inhibitors Antihypertensive standard
12 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB47422
ACE inhibitor from b-CN (48-59) rat
ACE inhibitors Antihypertensive
Cardiometabolic peptides
pep-lab Peptipedia AHTPDB AHTpin
standard
No
A 12-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from pep-lab, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
HSGIQSEPKAIP
Physicochemical Analysis
C55H90N16O18
RNDCLMFTWYV
IPS
1263.42
7.82
2
1
3
+0
4.93
-0.708
73.33
Mammalian: 3.5 hour Yeast: 10 min E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
1
Q
1
G
1
H
2
I
0
L
1
K
0
M
0
F
2
P
2
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 1 H: 1 I: 2 L: 0 K: 1 M: 0 F: 0 P: 2 S: 2 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12
C55H90N16O18
1263.42
7.82
+0
4.93
-0.708
1263.3959
1262.6598
Evidence Records 2 records
Evidence 1 Activity

Activity

EC50
ACE inhibitors
1001.00 µM
ACE inhibitor
ah

Source & Reference

NA
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

12
EC50>1000
Evidence 2 Activity

Activity

EC50
Antihypertensive
1001.00 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
12
EC50>1000
Additional Detail Fields 1 fields
12