Peptide record

TPDB47209

ACE inhibitor from beta-CN (104-120) ACE inhibitors Antihypertensive standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB47209
ACE inhibitor from beta-CN (104-120)
ACE inhibitors Antihypertensive
Cardiometabolic peptides
pep-lab Peptipedia AHTPDB AHTpin
standard
No
A 18-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from pep-lab, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
PKHKEMPFPPKYPVEPFT
Physicochemical Analysis
C105H153N23O25S1
ARNDCQGILSW
P
2169.57
9.58
4
2
5
+1
7.45
-1.211
16.11
Mammalian: >20 hour Yeast: >20 hour E.coli: ?
1490
68.68
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
2
E
0
Q
0
G
1
H
0
I
0
L
3
K
1
M
2
F
6
P
0
S
1
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 2 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 3 M: 1 F: 2 P: 6 S: 0 T: 1 W: 0 Y: 1 V: 1
Chemical Descriptors
18
C105H153N23O25S1
2169.57
9.58
+1
7.45
-1.211
2169.5374
2168.1093
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
0.00 µM
ACE inhibitor
ah

Source & Reference

NA
Hayes M., Stanton C., Fitzgerald G.F., Ross R.P.
Putting microbes to work: Dairy fermentation, cell factories and bioactive peptides. Part II: Bioactive peptide functions. Biotechnol. J., 2 (2007), 435–449.
2007
Journal

Other

18
Evidence 2 Activity

Activity

IC50
Antihypertensive
0.00 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Hayes M., Stanton C., Fitzgerald G.F., Ross R.P.
Putting microbes to work: Dairy fermentation, cell factories and bioactive peptides. Part II: Bioactive peptide functions. Biotechnol. J., 2 (2007), 435–449.
2007
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
18
Additional Detail Fields 1 fields
18