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Peptide record

TPDB47199

ACE inhibitor ACE inhibitors Antihypertensive standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB47199
ACE inhibitor
ACE inhibitors Antihypertensive
Cardiometabolic peptides
pep-lab Peptipedia AHTPDB AHTpin
standard
No
A 10-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from pep-lab, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
SKVYPFPGPI
Physicochemical Analysis
C55H81N11O13
ARNDCEQHLMTW
P
1104.31
9.74
1
0
4
+1
0.17
0.030
68.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
1490
134.93
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
0
L
1
K
0
M
1
F
3
P
1
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 0 K: 1 M: 0 F: 1 P: 3 S: 1 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
10
C55H81N11O13
1104.31
9.74
+1
0.17
0.030
1104.2943
1103.5996
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
1.70 µM
ACE inhibitor
ah

Source & Reference

NA
Korhonen H., Pihlanto A.
Technological options for the production of health-promoting proteins and peptides derived from milk and colostrum. Curr. Pharm. Des., 13,
2007
Journal

Other

10
IC50 (EC50) value in mg/mL
Evidence 2 Activity

Activity

IC50
Antihypertensive
1.70 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Korhonen H., Pihlanto A.
Technological options for the production of health-promoting proteins and peptides derived from milk and colostrum. Curr. Pharm. Des., 13,
2007
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
10
IC50 (EC50) value in mg/mL
Additional Detail Fields 1 fields
10