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Peptide record

TPDB47149

ACE inhibitor ACE inhibitors Antihypertensive standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB47149
ACE inhibitor
ACE inhibitors Antihypertensive
Cardiometabolic peptides
Peptipedia AHTPDB AHTpin
standard
No
A 9-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from Peptipedia, AHTPDB, and AHTpin, with an available 3D structural model.
Sequence
VYNEGLPAP
Physicochemical Analysis
C44H66N10O14
RDCQHIKMFSTW
P
959.07
3.29
0
1
4
-1
1.75
-0.233
86.67
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
1490
155.36
2
Residue Composition
number
1
A
0
R
1
N
0
D
0
C
1
E
0
Q
1
G
0
H
0
I
1
L
0
K
0
M
0
F
2
P
0
S
0
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 1 V: 1
Chemical Descriptors
9
C44H66N10O14
959.07
3.29
-1
1.75
-0.233
959.0508
958.4744
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
3.10 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001)
ACE inhibitor
ah

Source & Reference

NA
Liu X., Song C., Rui C., Jiang X., Yan J., Zou H.
Identification of angiotensin I-converting enzyme inhibitors in peptides mixture of hydrolyzed red deer plasma with proteomic approach. Chin. J. Chem., 28, 1665-1672
2010
Journal

Other

9
Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/) ID XM02-001
Evidence 2 Activity

Activity

IC50
Antihypertensive
3.10 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001)
ACE inhibitor
ah

Source & Reference

AHTPDB
Liu X., Song C., Rui C., Jiang X., Yan J., Zou H.
Identification of angiotensin I-converting enzyme inhibitors in peptides mixture of hydrolyzed red deer plasma with proteomic approach. Chin. J. Chem., 28, 1665-1672
2010
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
9
Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/) ID XM02-001
Additional Detail Fields 1 fields
9