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Peptide record

TPDB47144

ACE inhibitor from b-CN (49-59) mouse ACE inhibitors Antihypertensive standard
11 amino acids
Basic Information
3D PDB MODEL
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TPDB47144
ACE inhibitor from b-CN (49-59) mouse
ACE inhibitors Antihypertensive
Cardiometabolic peptides
pep-lab Peptipedia AHTPDB AHTpin
standard
No
A 11-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from pep-lab, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
SSIQSQPQAFT
Physicochemical Analysis
C51H80N14O19
RNDCEGHLKMWYV
QS
1193.28
6.02
0
0
3
-0
1.11
-0.555
44.55
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
7
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
3
Q
0
G
0
H
1
I
0
L
0
K
0
M
1
F
1
P
3
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 3 G: 0 H: 0 I: 1 L: 0 K: 0 M: 0 F: 1 P: 1 S: 3 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
11
C51H80N14O19
1193.28
6.02
-0
1.11
-0.555
1193.2601
1192.5705
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
1001.00 µM
ACE inhibitor
ah

Source & Reference

NA
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

11
EC50>1000
Evidence 2 Activity

Activity

IC50
Antihypertensive
1001.00 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
11
EC50>1000
Additional Detail Fields 1 fields
11