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Peptide record

TPDB47130

ACE inhibitor from b-CN (193-202) ACE inhibitors Antihypertensive standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB47130
ACE inhibitor from b-CN (193-202)
ACE inhibitors Antihypertensive
Cardiometabolic peptides
pep-lab Peptipedia AHTPDB AHTpin
standard
No
A 10-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from pep-lab, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
YQEPVLQPVR
Physicochemical Analysis
C56H89N15O16
ANDCGHIKMFSTW
QPV
1228.41
6.90
1
1
4
-0
3.53
-0.730
97.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
1490
121.29
3
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
1
E
2
Q
0
G
0
H
0
I
1
L
0
K
0
M
0
F
2
P
0
S
0
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 2 G: 0 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 1 V: 2
Chemical Descriptors
10
C56H89N15O16
1228.41
6.90
-0
3.53
-0.730
1228.3932
1227.6591
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
300.00 µM
ACE inhibitor
ah

Source & Reference

NA
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

10
Evidence 2 Activity

Activity

IC50
Antihypertensive
300.00 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
10
Additional Detail Fields 1 fields
10