Back to search

Peptide record

TPDB47111

ACE inhibitor from human plasma ACE inhibitors Antihypertensive standard
8 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB47111
ACE inhibitor from human plasma
ACE inhibitors Antihypertensive
Cardiometabolic peptides
pep-lab Peptipedia AHTPDB AHTpin
standard
No
A 8-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from pep-lab, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
YLYEIARR
Physicochemical Analysis
C50H78N14O13
NDCQGHKMFPSTWV
RY
1083.26
9.63
2
1
5
+1
0.72
-0.625
110.00
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
2980
275.10
2
Residue Composition
number
1
A
2
R
0
N
0
D
0
C
1
E
0
Q
0
G
0
H
1
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 2 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 2 V: 0
Chemical Descriptors
8
C50H78N14O13
1083.26
9.63
+1
0.72
-0.625
1083.2372
1082.5855
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
86.00 µM
ACE inhibitor
ah

Source & Reference

NA
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

8
Evidence 2 Activity

Activity

IC50
Antihypertensive
86.00 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
8
Additional Detail Fields 1 fields
8