Back to search

Peptide record

TPDB47095

ACE inhibitor from myosin light chain ACE inhibitors Antihypertensive standard
9 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB47095
ACE inhibitor from myosin light chain
ACE inhibitors Antihypertensive
Cardiometabolic peptides
Peptipedia AHTPDB AHTpin
standard
No
A 9-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from Peptipedia, AHTPDB, and AHTpin, with an available 3D structural model.
Sequence
RMLGQTPWK
Physicochemical Analysis
C50H81N15O12S1
ANDCEHIFSYV
RQGLKMPTW
1116.35
11.49
2
0
3
+2
0.34
-1.089
43.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
492.68
2
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
0
I
1
L
1
K
1
M
0
F
1
P
0
S
1
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 0 L: 1 K: 1 M: 1 F: 0 P: 1 S: 0 T: 1 W: 1 Y: 0 V: 0
Chemical Descriptors
9
C50H81N15O12S1
1116.35
11.49
+2
0.34
-1.089
1116.3343
1115.5892
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
34.00 µM
ACE inhibitor
ah

Source & Reference

NA
Katayama K., Jamhari, Mori T., Kawahara S., Miake K., Kodama Y., Sugiyama M., Kawamura Y., Nakayama T., Maruyama M., Muguruma M.
Angiotensin I-converting enzyme inhibitory peptide derived from porcine skeletal muscle myosin and its antihypertensive activity in spontaneously hypertensive rats. J. Food Sci., 72, 9, 702-706
2007
Journal

Other

9
Peptide derived from myosin light chain of Japanese domestic pork loin
Evidence 2 Activity

Activity

IC50
Antihypertensive
34.00 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Katayama K., Jamhari, Mori T., Kawahara S., Miake K., Kodama Y., Sugiyama M., Kawamura Y., Nakayama T., Maruyama M., Muguruma M.
Angiotensin I-converting enzyme inhibitory peptide derived from porcine skeletal muscle myosin and its antihypertensive activity in spontaneously hypertensive rats. J. Food Sci., 72, 9, 702-706
2007
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
9
Peptide derived from myosin light chain of Japanese domestic pork loin
Additional Detail Fields 1 fields
9