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Peptide record

TPDB47090

ACE inhibitor from myosin light chain ACE inhibitors Antihypertensive Neuropeptide standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB47090
ACE inhibitor from myosin light chain
ACE inhibitors Antihypertensive Neuropeptide
Cardiometabolic peptides Neuroactive peptides
pep-lab Peptipedia AHTPDB AHTpin
standard
No
A 8-aa standard natural multi-activity (ACE inhibitors, Antihypertensive, and Neuropeptide) peptide sequence curated from pep-lab, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
VKKVLGNP
Physicochemical Analysis
C39H71N11O10
ARDCEQHIMFSTWY
KV
854.06
10.60
2
0
3
+2
2.44
-0.138
121.25
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
1
L
2
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 2 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
8
C39H71N11O10
854.06
10.60
+2
2.44
-0.138
854.0459
853.5369
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
28.50 µM
ACE inhibitor
ah

Source & Reference

NA
Katayama K., Jamhari, Mori T., Kawahara S., Miake K., Kodama Y., Sugiyama M., Kawamura Y., Nakayama T., Maruyama M., Muguruma M.
Angiotensin I-converting enzyme inhibitory peptide derived from porcine skeletal muscle myosin and its antihypertensive activity in spontaneously hypertensive rats. J. Food Sci., 72, 9, 702-706
2007
Journal

Other

8
Peptide derived from myosin light chain of Japanese domestic pork loin
Evidence 2 Activity

Activity

IC50
Antihypertensive
28.50 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Katayama K., Jamhari, Mori T., Kawahara S., Miake K., Kodama Y., Sugiyama M., Kawamura Y., Nakayama T., Maruyama M., Muguruma M.
Angiotensin I-converting enzyme inhibitory peptide derived from porcine skeletal muscle myosin and its antihypertensive activity in spontaneously hypertensive rats. J. Food Sci., 72, 9, 702-706
2007
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
8
Peptide derived from myosin light chain of Japanese domestic pork loin
Additional Detail Fields 1 fields
8