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Peptide record

TPDB47083

ACE inhibitor from human plasma ACE inhibitors Antihypertensive standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB47083
ACE inhibitor from human plasma
ACE inhibitors Antihypertensive
Cardiometabolic peptides
pep-lab Peptipedia AHTPDB AHTpin
standard
No
A 7-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from pep-lab, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
YLYEIAR
Physicochemical Analysis
C44H66N10O12
NDCQGHKMFPSTWV
Y
927.07
6.84
1
1
5
-0
-0.09
-0.071
125.71
Mammalian: 2.8 hour Yeast: 10 min E.coli: 2 min
2980
321.44
2
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
1
E
0
Q
0
G
0
H
1
I
1
L
0
K
0
M
0
F
0
P
0
S
0
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 2 V: 0
Chemical Descriptors
7
C44H66N10O12
927.07
6.84
-0
-0.09
-0.071
927.0520
926.4846
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
16.00 µM
ACE inhibitor
ah

Source & Reference

NA
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

7
Evidence 2 Activity

Activity

IC50
Antihypertensive
16.00 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
7
Additional Detail Fields 1 fields
7