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Peptide record

TPDB47058

ACE inhibitor from yeast GADPH ACE inhibitors Antihypertensive standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB47058
ACE inhibitor from yeast GADPH
ACE inhibitors Antihypertensive
Cardiometabolic peptides
Peptipedia AHTPDB AHTpin
standard
No
A 9-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from Peptipedia, AHTPDB, and AHTpin, with an available 3D structural model.
Sequence
KKIATYQER
Physicochemical Analysis
C50H85N15O15
NDCGHLMFPSWV
K
1136.32
10.19
3
1
3
+2
4.11
-1.667
54.44
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
1490
131.13
3
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
1
E
1
Q
0
G
0
H
1
I
0
L
2
K
0
M
0
F
0
P
0
S
1
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 0 H: 0 I: 1 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 1 V: 0
Chemical Descriptors
9
C50H85N15O15
1136.32
10.19
+2
4.11
-1.667
1136.2980
1135.6330
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
2.00 µM
ACE inhibitor
ah

Source & Reference

NA
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

9
Evidence 2 Activity

Activity

IC50
Antihypertensive
2.00 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Meisel H., Walsh D. J., Murray B., FitzGerald R. J.
ACE inhibitory peptides. in: Nutraceutical proteins and peptides in health and disease. Mine Y., Shahidi F. (Eds.), CRC Taylor & Francis Group, Boca Raton, London, New York, 269-315.
2006
book

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
9
Additional Detail Fields 1 fields
9