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Peptide record

TPDB47053

ACE inhibitor from bullfrog (R.catesbeiana) ACE inhibitors Antihypertensive standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB47053
ACE inhibitor from bullfrog (R.catesbeiana)
ACE inhibitors Antihypertensive
Cardiometabolic peptides
pep-lab Peptipedia AHTPDB AHTpin
standard
No
A 12-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from pep-lab, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
GAAELPCSADWW
Physicochemical Analysis
C59H80N14O18S1
RNQHIKMFTYV
A
1305.43
3.01
0
2
6
-2
-1.17
0.008
57.50
Mammalian: 30 hour Yeast: >20 hour E.coli: >10 hour
11000
842.64
2
Residue Composition
number
3
A
0
R
0
N
1
D
1
C
1
E
0
Q
1
G
0
H
0
I
1
L
0
K
0
M
0
F
1
P
1
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 1 C: 1 E: 1 Q: 0 G: 1 H: 0 I: 0 L: 1 K: 0 M: 0 F: 0 P: 1 S: 1 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
12
C59H80N14O18S1
1305.43
3.01
-2
-1.17
0.008
1305.4124
1304.5477
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
0.95 µM
ACE inhibitor
ah

Source & Reference

NA
Qian Z.-L., Jung W.-K., Lee S.-H., Byun H.-G., Kim s.-K.
Antihypertensive effect of an angiotensin I-converting enzyme inhibitory peptide from bulfrog (Rana catesbeiana Shaw) muscle protein in spontaneously hypertensive rats. Process Biochemistry, 42, 1443-1448
2007
Journal

Other

12
Evidence 2 Activity

Activity

IC50
Antihypertensive
0.95 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Qian Z.-L., Jung W.-K., Lee S.-H., Byun H.-G., Kim s.-K.
Antihypertensive effect of an angiotensin I-converting enzyme inhibitory peptide from bulfrog (Rana catesbeiana Shaw) muscle protein in spontaneously hypertensive rats. Process Biochemistry, 42, 1443-1448
2007
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
12
Additional Detail Fields 1 fields
12