Peptide record

TPDB46986

ACE inhibitor from b-casein (169-174) ACE inhibitors Antihypertensive standard
6 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB46986
ACE inhibitor from b-casein (169-174)
ACE inhibitors Antihypertensive
Cardiometabolic peptides
pep-lab Peptipedia AHTPDB AHTpin
standard
No
A 6-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from pep-lab, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
KVLPVP
Physicochemical Analysis
C32H57N7O7
ARNDCEQGHIMFSTWY
PV
651.85
10.10
1
0
3
+1
1.47
0.850
161.67
Mammalian: 1.3 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
1
K
0
M
0
F
2
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 1 M: 0 F: 0 P: 2 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
6
C32H57N7O7
651.85
10.10
+1
1.47
0.850
651.8354
651.4306
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
5.00 µM
ACE inhibitor
ah

Source & Reference

NA
Maeno M., Yamamoto N., Takano T.
Identification of antihypertensive peptides from casein hydrolysate produced by proteinase from Lactobacillus helveticus. J.Dairy Sci., 73, 1316-1321
1996
Journal

Other

6
Evidence 2 Activity

Activity

IC50
Antihypertensive
5.00 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Maeno M., Yamamoto N., Takano T.
Identification of antihypertensive peptides from casein hydrolysate produced by proteinase from Lactobacillus helveticus. J.Dairy Sci., 73, 1316-1321
1996
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
6
Additional Detail Fields 1 fields
6