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Peptide record

TPDB46973

ACE inhibitor from edible mushroom (Hypsizygus marmoreus) ACE inhibitors Antihypertensive standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB46973
ACE inhibitor from edible mushroom (Hypsizygus marmoreus)
ACE inhibitors Antihypertensive
Cardiometabolic peptides
pep-lab Peptipedia AHTPDB AHTpin
standard
No
A 10-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from pep-lab, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
LSMGSASLSP
Physicochemical Analysis
C39H68N10O15S1
RNDCEQHIKFTWYV
S
949.09
6.02
0
0
4
-0
-0.54
0.610
88.00
Mammalian: 5.5 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
2
L
0
K
1
M
0
F
1
P
4
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 2 K: 0 M: 1 F: 0 P: 1 S: 4 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
10
C39H68N10O15S1
949.09
6.02
-0
-0.54
0.610
949.0786
948.4570
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
0.19 µM
ACE inhibitor
ah

Source & Reference

NA
Kang M.-G., Kim Y.-H., Bolormaa Z., Kim M.-K., Seo G.-S., Lee J.-S.
Characterization of an Antihypertensive Angiotensin I-Converting Enzyme Inhibitory Peptide from the Edible Mushroom Hypsizygus marmoreus. BioMed Research International, doi: 10.1155/2013/283964.
2013
Journal

Other

10
Activity expressed in (mg/mL).
Evidence 2 Activity

Activity

IC50
Antihypertensive
0.19 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Kang M.-G., Kim Y.-H., Bolormaa Z., Kim M.-K., Seo G.-S., Lee J.-S.
Characterization of an Antihypertensive Angiotensin I-Converting Enzyme Inhibitory Peptide from the Edible Mushroom Hypsizygus marmoreus. BioMed Research International, doi: 10.1155/2013/283964.
2013
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
10
Activity expressed in (mg/mL).
Additional Detail Fields 1 fields
10