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Peptide record

TPDB46936

ACE inhibitor ACE inhibitors Antihypertensive standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB46936
ACE inhibitor
ACE inhibitors Antihypertensive
Cardiometabolic peptides
pep-lab Peptipedia AHTPDB AHTpin
standard
No
A 8-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from pep-lab, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
QLGFLGPR
Physicochemical Analysis
C41H66N12O10
ANDCEHIKMSTWYV
GL
887.05
11.05
1
0
3
+1
-0.39
0.000
97.50
Mammalian: 0.8 hour Yeast: 10 min E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
1
Q
2
G
0
H
0
I
2
L
0
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 0 L: 2 K: 0 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C41H66N12O10
887.05
11.05
+1
-0.39
0.000
887.0345
886.5010
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
148.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001)
ACE inhibitor
ah

Source & Reference

NA
Lee J. K., Jeon J.-K., Byun H.-G.
Effect of angiotensin-converting enzyme inhibitory peptide purified from skate skin hydrolysate. Food Chem., 125, 495-499, 2011
2011
Journal

Other

8
Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/) ID: XM02-001
Evidence 2 Activity

Activity

IC50
Antihypertensive
148.00 µM
Inhibitor of Angiotensin-Converting Enzyme (ACE) (EC 3.4.15.1) (MEROPS ID: XM02-001)
ACE inhibitor
ah

Source & Reference

AHTPDB
Lee J. K., Jeon J.-K., Byun H.-G.
Effect of angiotensin-converting enzyme inhibitory peptide purified from skate skin hydrolysate. Food Chem., 125, 495-499, 2011
2011
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
8
Information concerning Angiotensin-Converting Enzyme (ACE) is available in MEROPS database of proteolytic enzymes (http://merops.sanger.ac.uk/) ID: XM02-001
Additional Detail Fields 1 fields
8