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Peptide record

TPDB46918

ACE inhibitor from k-CN (fr. 12-17) ACE inhibitors Antihypertensive standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB46918
ACE inhibitor from k-CN (fr. 12-17)
ACE inhibitors Antihypertensive
Cardiometabolic peptides
pep-lab Peptipedia AHTPDB AHTpin
standard
No
A 6-aa standard natural multi-activity (ACE inhibitors and Antihypertensive) peptide sequence curated from pep-lab, Peptipedia, AHTPDB, and other sources, with an available 3D structural model.
Sequence
EKDERF
Physicochemical Analysis
C35H54N10O13
ANCQGHILMPSTWYV
E
822.87
4.44
2
3
1
-1
5.94
-2.683
0.00
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
1
D
0
C
2
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 1 C: 0 E: 2 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
6
C35H54N10O13
822.87
4.44
-1
5.94
-2.683
822.8603
822.3859
Evidence Records 2 records
Evidence 1 Activity

Activity

IC50
ACE inhibitors
14.30 µM
ACE inhibitor
ah

Source & Reference

NA
Gomez-Ruiz J. A., Ramos M., Recio I.
Identification of novel angiotensin-converting enzyme-inhibitory peptides from ovine milk proteins by CE-MS and chromatographic techniques. Electrophoresis, 28, 4202-4211.
2007
Journal

Other

6
Evidence 2 Activity

Activity

IC50
Antihypertensive
14.30 µM
ACE inhibitor
ah

Source & Reference

AHTPDB
Gomez-Ruiz J. A., Ramos M., Recio I.
Identification of novel angiotensin-converting enzyme-inhibitory peptides from ovine milk proteins by CE-MS and chromatographic techniques. Electrophoresis, 28, 4202-4211.
2007
Journal

Other

Source Activity Label Source Definition
Antihypertensive
AHTPDB manually curated experimentally validated antihypertensive peptide annotation.
6
Additional Detail Fields 1 fields
6