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Peptide record

TPDB45821

Antiviral standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB45821
Antiviral
Anti-infective peptides
DRAVP 2.0
standard
No
A 19-aa standard natural antiviral peptide sequence curated from DRAVP 2.0, with an available 3D structural model.
Sequence
FLPIIINLKALAALAKKIL
Physicochemical Analysis
C102H179N23O21
RDCEQGHMSTWYV
L
2063.68
10.84
3
0
14
+3
-2.01
1.589
205.79
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
4
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
4
I
5
L
3
K
0
M
1
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 4 L: 5 K: 3 M: 0 F: 1 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
19
C102H179N23O21
2063.68
10.84
+3
-2.01
1.589
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antiviral
10-20 µM

Target

B. subtilis ATCC 6633

Source & Reference

DRAVP 2.0

Other

Active against B. subtilis ATCC 6633 (MIC 10-20 uM), E. faecalis ATCC 12953 (MIC 1-10 uM), S. aureus ATCC 29213 or MRSA ATCC 33591 or MRSA #S
Evidence 2 Activity

Activity

MIC
Antiviral
1-10 µM

Target

Enterococcus faecalis ATCC 12953

Source & Reference

DRAVP 2.0

Other

Active against B. subtilis ATCC 6633 (MIC 10-20 uM), E. faecalis ATCC 12953 (MIC 1-10 uM), S. aureus ATCC 29213 or MRSA ATCC 33591 or MRSA #SAP0017 (MIC 10-30 uM), S. pyogenes ATC
Evidence 3 Activity

Activity

MIC
Antiviral
1-10 µM

Target

Streptococcus pyogenes ATCC 19615

Source & Reference

DRAVP 2.0

Other

3 (MIC 1-10 uM), S. aureus ATCC 29213 or MRSA ATCC 33591 or MRSA #SAP0017 (MIC 10-30 uM), S. pyogenes ATCC 19615 (MIC 1-10 uM), E. coli ATCC8739 or 1812446 KPC-positive or 2101123 or 0157 (MIC 10-20 uM), K. pneumonia
Evidence 4 Activity

Activity

MIC
Antiviral
10-20 µM

Target

Escherichia coli ATCC8739 or 1812446 KPC-positive or 2101123 or 0157

Source & Reference

DRAVP 2.0

Other

or MRSA ATCC 33591 or MRSA #SAP0017 (MIC 10-30 uM), S. pyogenes ATCC 19615 (MIC 1-10 uM), E. coli ATCC8739 or 1812446 KPC-positive or 2101123 or 0157 (MIC 10-20 uM), K. pneumoniae ATCC 13885 or 1825971 KPC (MIC 20-30 uM), P. mirabilis ATCC25933 (MIC 10-2
Evidence 5 Activity

Activity

MIC
Antiviral
20-30 µM

Target

Klebsiella pneumoniae ATCC 13885 or 1825971 KPC

Source & Reference

DRAVP 2.0

Other

MIC 1-10 uM), E. coli ATCC8739 or 1812446 KPC-positive or 2101123 or 0157 (MIC 10-20 uM), K. pneumoniae ATCC 13885 or 1825971 KPC (MIC 20-30 uM), P. mirabilis ATCC25933 (MIC 10-20 uM), P. aeruginosa ATCC15442 (MIC 10-20 uM), and S. en
Evidence 6 Activity

Activity

MIC
Antiviral
10-20 µM

Target

P. mirabilis ATCC25933

Source & Reference

DRAVP 2.0

Other

r 2101123 or 0157 (MIC 10-20 uM), K. pneumoniae ATCC 13885 or 1825971 KPC (MIC 20-30 uM), P. mirabilis ATCC25933 (MIC 10-20 uM), P. aeruginosa ATCC15442 (MIC 10-20 uM), and S. enterica ATCC 14028 (MIC 10-20 uM). Virus
Evidence 7 Activity

Activity

MIC
Antiviral
10-20 µM

Target

Pseudomonas aeruginosa ATCC15442

Source & Reference

DRAVP 2.0

Other

eumoniae ATCC 13885 or 1825971 KPC (MIC 20-30 uM), P. mirabilis ATCC25933 (MIC 10-20 uM), P. aeruginosa ATCC15442 (MIC 10-20 uM), and S. enterica ATCC 14028 (MIC 10-20 uM). Virus: Inhibited entry of Human alphaherpesvi
Evidence 8 Activity

Activity

MIC
Antiviral
10-20 µM

Target

S. enterica ATCC 14028

Source & Reference

DRAVP 2.0

Other

0 uM), P. mirabilis ATCC25933 (MIC 10-20 uM), P. aeruginosa ATCC15442 (MIC 10-20 uM), and S. enterica ATCC 14028 (MIC 10-20 uM). Virus: Inhibited entry of Human alphaherpesvirus 1 (HSV-1) (EC50 6.68 uM).